ANABOLIC TREATMENTS FOR OSTEOPOROSIS

Boca Raton - New York - London - Tokyo: CRC Press, 1998. First Printing . Printed Coated Boards. Near Fine/No Jacket. 9 1/2" Tall. In these chapters we tell the exciting story of the emerging anabolic strategies for treating osteoporosis. We start with a fresh look at the intricacies of bone biology, osteopenia, and osteoporosis. We then turn to the anabolic agents and their intracellular mediators that hopefully will soon be the star players in the treatment of osteoporosis." [Preface] The chapter headings (and authors) are: Osteoporoses: Their Nature and Terapeutic Targets (Frost); Osteoporosis - Mechanisms and Models (Mosekilde); PTH: Skeletal Effects in the Ovariectomized Rat Model for Postmenopausal Bone Loss (Wronski & Li); Parathyroid Hormone: The Clinical Experience and Prospects (Hodsman, Fraher, & Watson); Bone Formation May Be Uncoupled from Resrption, as Demonstrated by a new class of hPTHrP-(I-34) Analogues in Both Rapid and Slow Turnover Models of Osteopenia (Vickery, Avnur, et al.); Commercial Exploitation of Parathyroid Hormone Therapy for the Treatment of Postmenopausal Osteoporoses (Marchand); The Insulin-Like Growth Factors: Potential Anabolic Agents for the Skeleton (Johansson & Rosen); and Osteogenic Actions of Fluoride: Its Therapeutic Use for Established Osteoporosis (Lau, Akesson, et al.). 266 pages, with tables, figures, and Index; plus about 10 unnumbered pages prefatory matter including Contributors, and Table of Contents; References at the end of each chapter. Boards have small push at front lower lagging corner, otherwise clean and sound; text is strong, and clean, excepting a blemish on title page..