Genetically Engineered Mice for Cancer Research: Design, Analysis, Pathways, Validation and Pre-Clinical Testing Tapa dura - 2011 - 2012th Edición
de Jeffrey E. Green (Editor); Thomas Ried (Editor)
Descripción de contraportada
Technological advances in manipulating the mouse genome has led to the development of sophisticated genetically-engineered models of human cancer that recapitulate many molecular, biologic and histologic features of human tumors. This book provides an overview of the design considerations and technical approaches used to generate these important models of human cancer. These models are designed to recapitulate molecular aberrations in target organs known to drive human cancers. State-of-the-art methods to analyze genome and transcriptome alterations in these models and particular relationships to human cancers are presented. Mouse-human comparisons of tumor pathologies are exemplified. Criteria for selecting relevant models for preclinical studies that might be translatable to the treatment of human cancers are discussed. The topics presented in this book will be invaluable to both newcomers to the field as well as established investigators who use genetically-engineered mouse models to study the development, progression and treatment of cancer.
Detalles
- Título Genetically Engineered Mice for Cancer Research: Design, Analysis, Pathways, Validation and Pre-Clinical Testing
- Autor Jeffrey E. Green (Editor); Thomas Ried (Editor)
- Encuadernación Tapa dura
- Número de edición 2012th
- Edición 2012
- Páginas 632
- Volúmenes 1
- Idioma ENG
- Editorial Springer
- Fecha de publicación 2011-12-08
- Ilustrado Sí
- Features Bibliography, Illustrated, Index
- ISBN 9780387698038 / 0387698035
- Peso 2.15 libras (0.98 kg)
- Dimensiones 9.2 x 6.1 x 1.5 pulgadas (23.37 x 15.49 x 3.81 cm)
- Library of Congress subjects Transgenic mice, Mice as laboratory animals
- Número de catálogo de la Librería del Congreso de EEUU 2011939084
- Dewey Decimal Code 573.44
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Genetically Engineered Mice for Cancer Research: Design, Analysis, Pathways, Validation and Pre-Clinical Testing
de Jeffrey E. Green & Thomas Ried (editors)
- Usado
- Muy bueno
- Tapa dura
- First
- Estado
- Usado - Muy bueno
- Edición
- 1st Edition
- Encuadernación
- Hardcover
- ISBN 10 / ISBN 13
- 9780387698038 / 0387698035
- Cantidad disponible
- 1
- Librería
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Dover, Kent, United Kingdom
- Precio
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EUR 29.72EUR 27.35 enviando a USA