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Enzyme Systems That Metabolise Drugs and Other Xenobiotics
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Enzyme Systems That Metabolise Drugs and Other Xenobiotics Tapa dura - 2001

de Costas Ioannides (Editor)


Información de la editorial

In den letzten Jahren haben wir neue Erkenntnisse ber metabolische und toxikologische Aspekte metabolisierender Enzymsysteme gewonnen. Dieser Band gehrt zur Reihe 'Current Toxicology Series' und ist das erste ma gebliche Nachschlagewerk, das sich kritisch mit Enzymsystemen auseinandersetzt, die am Metabolismus von Chemikalien und anderer Xenobiotika beteiligt sind. Ein deutlicher Schwerpunkt liegt dabei auf dem Medikamentenstoffwechsel. Jedes Kapitel behandelt ein spezifisches Enzymsystem und diskutiert detailliert die metabolischen und toxikologischen Aspekte des metabolisierenden Enzymsystems. Das "Handbook of Enzyme Systems for Drugs and other Xenobiotics" ist eine einzigartige Informationsquelle, denn es setzt sich speziell mit dem Thema der Wirkstoff-Forschung und -Entwicklung auseinander. Geschrieben von fhrenden internationalen Experten auf diesem Gebiet.

Primera línea

The meteoric advances in analytical technology that occurred during the last two decades have made possible the analysis of complex mixtures and the determination of chemicals present in minute quantities, thus allowing us to appreciate for the first time the number and diversity of chemicals to which we are exposed, from conception to death.

Descripción de contraportada

This definitive reference work describes in detail the enzyme systems that participate in the metabolism of xenobiotics, particularly medicinal drugs. Each chapter focuses on a specific enzyme system, emphasising its role in the activation and detoxication of chemicals. Aspects discussed critically include:
* enzyme function in the metabolism and bioactivation of xenobiotics

* substrate specificity

* tissue distribution

* species distribution (to include laboratory animals and humans)

* hormonal regulation

* sex differences

* modulation by prior exposure to other chemicals

* age-dependent expression

* pharmacogenetics and modulation by disease.
Enzyme Systems that Metabolise Drugs and Other Xenobiotics will be essential reading for industrial research scientists working in the fine chemicals and pharmaceutical industries, especially those concerned with the safety evaluation of chemicals, and investigating their metabolism, pharmacokinetic characteristics and toxicological properties. The nature and scope of the book will also make it attractive to the research toxicologist and to postgraduate students studying toxicology, as well as to clinicians and pharmacists.

Detalles

  • Título Enzyme Systems That Metabolise Drugs and Other Xenobiotics
  • Autor Costas Ioannides (Editor)
  • Encuadernación Tapa dura
  • Edición First
  • Páginas 588
  • Volúmenes 1
  • Idioma ENG
  • Editorial John Wiley & Sons
  • Fecha de publicación 2001-12-21
  • Ilustrado
  • Features Illustrated, Index, Table of Contents
  • ISBN 9780471894667 / 0471894664
  • Peso 2.1 libras (0.95 kg)
  • Dimensiones 9 x 6 x 1.25 pulgadas (22.86 x 15.24 x 3.18 cm)
  • Library of Congress subjects Drugs - Metabolism, Xenobiotics - Metabolism
  • Número de catálogo de la Librería del Congreso de EEUU 2001039011
  • Dewey Decimal Code 615.7

Acerca del autor

Costas Ioannides is the author of Enzyme Systems that Metabolise Drugs and Other Xenobiotics, published by Wiley.
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Enzyme Systems That Metabolise Drugs and Other Xenobiotics
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Enzyme Systems That Metabolise Drugs and Other Xenobiotics

de Ioannides, Costas (Editor)

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John Wiley & Sons Inc, 2002. Hardcover. New. 1st edition. 578 pages. 9.25x6.25x1.50 inches.
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Enzyme Systems That Metabolise Drugs and Other Xenobiotics
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Enzyme Systems That Metabolise Drugs and Other Xenobiotics

de Costas Ioannides

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ISBN 10 / ISBN 13
9780471894667 / 0471894664
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John Wiley & Sons , pp. viii + 578 Index. Hardback. New.
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Enzyme Systems that Metabolise Drugs and Other Xenobiotics
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Enzyme Systems that Metabolise Drugs and Other Xenobiotics

de Ioannides, Costas

  • Nuevo
  • Tapa dura
Estado
Nuevo
Encuadernación
Hardcover
ISBN 10 / ISBN 13
9780471894667 / 0471894664
Cantidad disponible
1
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San Diego, California, United States
Puntuación del vendedor:
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Wiley, 2001-12-21. Hardcover. New. New. In shrink wrap. Looks like an interesting title!
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