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Enzyme Systems That Metabolise Drugs and Other Xenobiotics Tapa dura - 2001
de Costas Ioannides (Editor)
Primera línea
The meteoric advances in analytical technology that occurred during the last two decades have made possible the analysis of complex mixtures and the determination of chemicals present in minute quantities, thus allowing us to appreciate for the first time the number and diversity of chemicals to which we are exposed, from conception to death.
Descripción de contraportada
This definitive reference work describes in detail the enzyme systems that participate in the metabolism of xenobiotics, particularly medicinal drugs. Each chapter focuses on a specific enzyme system, emphasising its role in the activation and detoxication of chemicals. Aspects discussed critically include:
* enzyme function in the metabolism and bioactivation of xenobiotics
* substrate specificity
* tissue distribution
* species distribution (to include laboratory animals and humans)
* hormonal regulation
* sex differences
* modulation by prior exposure to other chemicals
* age-dependent expression
* pharmacogenetics and modulation by disease.
Enzyme Systems that Metabolise Drugs and Other Xenobiotics will be essential reading for industrial research scientists working in the fine chemicals and pharmaceutical industries, especially those concerned with the safety evaluation of chemicals, and investigating their metabolism, pharmacokinetic characteristics and toxicological properties. The nature and scope of the book will also make it attractive to the research toxicologist and to postgraduate students studying toxicology, as well as to clinicians and pharmacists.
Detalles
- Título Enzyme Systems That Metabolise Drugs and Other Xenobiotics
- Autor Costas Ioannides (Editor)
- Encuadernación Tapa dura
- Edición First
- Páginas 588
- Volúmenes 1
- Idioma ENG
- Editorial John Wiley & Sons
- Fecha de publicación 2001-12-21
- Ilustrado Sí
- Features Illustrated, Index, Table of Contents
- ISBN 9780471894667 / 0471894664
- Peso 2.1 libras (0.95 kg)
- Dimensiones 9 x 6 x 1.25 pulgadas (22.86 x 15.24 x 3.18 cm)
- Library of Congress subjects Drugs - Metabolism, Xenobiotics - Metabolism
- Número de catálogo de la Librería del Congreso de EEUU 2001039011
- Dewey Decimal Code 615.7
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Enzyme Systems that Metabolise Drugs and Other Xenobiotics
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- ISBN 10 / ISBN 13
- 9780471894667 / 0471894664
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Enzyme Systems That Metabolise Drugs and Other Xenobiotics
de Ioannides, Costas (Editor)
- Nuevo
- Tapa dura
- Estado
- Nuevo
- Encuadernación
- Hardcover
- ISBN 10 / ISBN 13
- 9780471894667 / 0471894664
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- 2
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Exeter, Devon, United Kingdom
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EUR 539.74EUR 11.98 enviando a USA
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Enzyme Systems That Metabolise Drugs and Other Xenobiotics
de Costas Ioannides
- Nuevo
- Tapa dura
- Estado
- Nuevo
- Encuadernación
- Hardcover
- ISBN 10 / ISBN 13
- 9780471894667 / 0471894664
- Cantidad disponible
- 3
- Librería
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Woodside, New York, United States
- Precio
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EUR 511.63EUR 3.77 enviando a USA
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Enzyme Systems that Metabolise Drugs and Other Xenobiotics
de Ioannides, Costas
- Nuevo
- Tapa dura
- Estado
- Nuevo
- Encuadernación
- Hardcover
- ISBN 10 / ISBN 13
- 9780471894667 / 0471894664
- Cantidad disponible
- 1
- Librería
-
San Diego, California, United States
- Precio
-
EUR 553.17EUR 5.15 enviando a USA