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G Proteins, Receptors, and Disease
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G Proteins, Receptors, and Disease Tapa blanda - 2012

de Allen M. Spiegel (Editor)


Descripción de contraportada

More than a collection of review articles, G Proteins, Receptors, and Disease summarizes in depth the state of our knowledge today concerning not only how cells communicate via G-protein-coupled signal transduction processes, but also how defects in these proteins and their receptors can cause serious human disease involving many different organ systems. Written by leading investigators, each chapter describes in detail the structure and function of a particular G protein or receptor, outlines possible mutations, and discusses fully the molecular pathogenesis of associated diseases. Diagnostic and therapeutic implications are also discussed when relevant.

In its unique blend of cutting-edge basic science and clinical medicine, G Proteins, Receptors, and Disease offers deep insights into the physiological significance of this key signal transduction pathway, as well as into the molecular basis of diseases ranging from obesity to malignancy. The basic understanding of the complex signal transduction process achieved here provides a firm foundation for future efforts to prevent and cure these diseases.

Detalles

  • Título G Proteins, Receptors, and Disease
  • Autor Allen M. Spiegel (Editor)
  • Encuadernación Tapa blanda
  • Edición Softcover reprin
  • Páginas 324
  • Volúmenes 1
  • Idioma ENG
  • Editorial Humana
  • Fecha de publicación 2012-10-09
  • ISBN 9781461272908 / 1461272904
  • Peso 1.3 libras (0.59 kg)
  • Dimensiones 10 x 7 x 0.71 pulgadas (25.40 x 17.78 x 1.80 cm)
  • Dewey Decimal Code 616.407
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G Proteins, Receptors, and Disease

G Proteins, Receptors, and Disease

de Allen M. Spiegel

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ISBN 10 / ISBN 13
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G Proteins, Receptors, and Disease
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G Proteins, Receptors, and Disease

de Allen M. Spiegel

  • Nuevo
  • Tapa blanda
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Paperback
ISBN 10 / ISBN 13
9781461272908 / 1461272904
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Paperback / softback. New.
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G Proteins, Receptors, and Disease
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G Proteins, Receptors, and Disease

de Allen M. Spiegel

  • Nuevo
Estado
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ISBN 10 / ISBN 13
9781461272908 / 1461272904
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10
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Southport, Merseyside, United Kingdom
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New. "Theoretically, one should obtain essentially the same clinical picture from failure of an end-organ to respond to a hormone as from a decreased production or absence of said hormone. " With these words, Fuller Albright began his now classic paper describing a novel disease, pseudo hypoparathyroidism (PHP), and a novel concept, hormone resis- tance as a cause of disease. Soon, other hormone resistance disorders such as nephrogenic diabetes insipidus (NDI) were recognized, and the concept was extended to resistance to other substances such as calcium ions in familial hypocalciuric hypercalcemia (FHH). Later, diseases characterized by excess rather than deficient hormone action such as McCune-Albright syndrome (MAS) and familial male precocious puberty (FMPP) were recognized to be caused by autonomous endocrine hyperfunction. Although many i!!vestigators provided careful and detailed descriptions of the clinical features of these and other related endocrine disorders, an… Leer más
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G Proteins, Receptors, and Disease (Contemporary Endocrinology)
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G Proteins, Receptors, and Disease (Contemporary Endocrinology)

de Spiegel, Allen M. (Editor)

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Humana Press, 2012. Paperback. New. reprint edition. 336 pages. 9.90x7.30x0.90 inches.
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