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Macrophages: Biology and Role in the Pathology of Diseases Tapa dura - 2014 - 1st Edición
de Subhra K. Biswas (Editor); Alberto Mantovani (Editor)
Descripción de contraportada
Macrophages are a key component of the innate immune system and play an integral role in host defense and homeostasis. On one hand, these cells contribute to host defence by triggering inflammation, displaying microbicidal/tumoricidal properties, regulating the activation of adaptive immunity and promoting resolution of inflammation. On the other hand, they contribute to essential trophic functions such as neural patterning, bone morphogenesis and ductal branching in mammary glands. Thus, macrophages are extremely versatile cells that can respond efficiently to tissue microenvironmental cues by polarizing to distinct phenotypes, depending on the functions they need to perform. Indeed, functional diversity and plasticity are hallmarks of these cells.
Macrophages may also play a detrimental role. An overwhelming body of literature has indicated their crucial role in pathogenesis. The list includes sepsis, cancer, metabolic syndrome, immunodeficiency, auto-immune disease- virtually impacting every major pathology that we know. These observations have suggested macrophages and their related molecules as potential targets in therapeutic applications. Available evidence proclaims macrophages as a key player in homeostasis, host defense and disease. Crucial developments in the past few years call for a re-evaluation and update of our understanding of macrophages. The present book is an endeavour that attempts to provide state-of-the art knowledge of these cells in health and disease.
Detalles
- Título Macrophages: Biology and Role in the Pathology of Diseases
- Autor Subhra K. Biswas (Editor); Alberto Mantovani (Editor)
- Encuadernación Tapa dura
- Número de edición 1st
- Edición 1
- Páginas 615
- Volúmenes 1
- Idioma ENG
- Editorial Springer
- Fecha de publicación 2014-11-13
- Ilustrado Sí
- Features Bibliography, Illustrated
- ISBN 9781493913107 / 1493913107
- Peso 2.31 libras (1.05 kg)
- Dimensiones 9.21 x 6.14 x 1.31 pulgadas (23.39 x 15.60 x 3.33 cm)
-
Temas
- Aspects (Academic): Medical/Medicine Aspects
- Library of Congress subjects Macrophages, Macrophages - Physiology
- Número de catálogo de la Librería del Congreso de EEUU 2014950049
- Dewey Decimal Code 571.967
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Macrophages: Biology and Role in the Pathology of Diseases
de Subhra K. Biswas
- Nuevo
- Tapa dura
- Estado
- Nuevo
- Encuadernación
- Hardcover
- ISBN 10 / ISBN 13
- 9781493913107 / 1493913107
- Cantidad disponible
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- Librería
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Uxbridge, Greater London, United Kingdom
- Precio
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EUR 220.42EUR 9.57 enviando a USA
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![Macrophages: Biology and Role in the Pathology of Diseases](https://d3525k1ryd2155.cloudfront.net/f/107/913/9781493913107.IN.0.m.jpg)
Macrophages: Biology and Role in the Pathology of Diseases
de Biswas, Subhra K. (Edited by)/ Mantovani, Alberto (Edited by)
- Nuevo
- Tapa dura
- Estado
- Nuevo
- Encuadernación
- Hardcover
- ISBN 10 / ISBN 13
- 9781493913107 / 1493913107
- Cantidad disponible
- 2
- Librería
-
Exeter, Devon, United Kingdom
- Precio
-
EUR 271.03EUR 11.98 enviando a USA