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G Protein Signaling: Methods and Protocols Tapa blanda - 2010
de Alan V. Smrcka (Editor)
Descripción de contraportada
G proteins and G protein-coupled receptors are ubiquitously expressed proteins that regulate a wide range of physiological processes and are consequently the targets of many pharmaceuticals. In G Protein Signaling: Methods and Protocols, leading researchers describe in detail key methods for investigating G protein signaling from a variety of perspectives ranging from in vitro biochemistry to whole animal studies. The authors focus on the mechanisms of G protein and G protein-coupled receptor function and the roles of G protein subunits in cell biology and disease. Among the readily reproducible techniques presented are those for the purification of G proteins and effector enzymes, assays of these purified G proteins and effector enzymes, and for the study of G protein interactions with effectors in intact cells. Additional methods are provided for assaying G protein-coupled receptor structure, function, and localization, for studying the physiological roles for endogenous G proteins, and for examining lipid and phosphate modifications of RGS proteins. Each fully tested protocol includes a background introduction explaining the principle behind the technique, equipment and reagent lists, tips on troubleshooting and avoiding known pitfalls, and, where needed, a discussion of the interpretation and use of results.
Comprehensive and highly practical, G Protein Signaling: Methods and Protocols offers novice and expert researchers alike an array of cutting-edge tools to illuminate the roles of G protein and G protein-coupled receptors, as well as a better understanding of their action with drugs, neurotransmitters, and sensory stimuli.
Detalles
- Título G Protein Signaling: Methods and Protocols
- Autor Alan V. Smrcka (Editor)
- Encuadernación Tapa blanda
- Edición Softcover reprin
- Páginas 250
- Volúmenes 1
- Idioma ENG
- Editorial Humana
- Fecha de publicación 2010
- ISBN 9781617373817 / 1617373818
- Peso 0.84 libras (0.38 kg)
- Dimensiones 9.02 x 5.98 x 0.6 pulgadas (22.91 x 15.19 x 1.52 cm)
- Dewey Decimal Code 572.643
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G Protein Signaling
- Nuevo
- Estado
- Nuevo
- ISBN 10 / ISBN 13
- 9781617373817 / 1617373818
- Cantidad disponible
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Woodside, New York, United States
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EUR 133.16EUR 3.78 enviando a USA
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![G Protein Signaling: Methods and Protocols](https://d3525k1ryd2155.cloudfront.net/f/817/373/9781617373817.IN.0.m.jpg)
G Protein Signaling: Methods and Protocols
de Smrcka, Alan V. (Editor)
- Nuevo
- Tapa blanda
- Estado
- Nuevo
- Encuadernación
- Paperback
- ISBN 10 / ISBN 13
- 9781617373817 / 1617373818
- Cantidad disponible
- 1
- Librería
-
Exeter, Devon, United Kingdom
- Precio
-
EUR 171.06EUR 11.98 enviando a USA