Descripción:
Royal Society of Chemistry, 2012. 1 ST. Hardcover. New/New.
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Kinase Drug Discovery Tapa dura - 2012 - 1st Edición
de Richard A. Ward (Editor); Frederick W. Goldberg (Editor); Cancer Research Uk (Other)
Although there have been a number of reviews/publications on kinase research, this book fills a gap in the literature by considering the current and future opportunities and challenges in targeting this important family of enzymes. The book is forward-looking and identifies a number of hot topics and key areas for kinase drug discovery over the coming years.
Descripción de contraportada
Kinase drug discovery remains an area of significant interest across the pharmaceutical industry and academia. There are currently 13 FDA-approved small molecule drugs and over 500 small molecules in active development targeting kinases. These agents have delivered significant benefits to patients that can be measured in life extension or improvement in the quality of life in diseases like cancer and inflammation. The kinase family has therefore been a rich source of new targets and opportunities for the pharmaceutical industry but has also presented significant and unique challenges. Although there have been a number of books on kinase research, this book focuses on the future opportunities and challenges, rather than on case studies of specific targets. The editors have also aimed to cover broad themes on a number of hot topics in current kinase drug discovery. Highly respected authors in the field have been identified with a combined drug discovery experience of over 200 years. Areas covered include an insight into how medicinal chemistry has been able to exploit this unique target class, along with reflections on the varied mechanisms of kinase inhibitors. Also addressed is resistance to kinase inhibition caused by amino acid mutations, non-protein kinases and applications beyond the human kinome into parasitic diseases. Modern approaches to finding kinase leads and reflections on how the field may progress over coming years are also described. This book will be of great interest to pharmaceutical scientists, biologists and medicinal chemists working in drug discovery and drug development.
Detalles
- Título Kinase Drug Discovery
- Autor Richard A. Ward (Editor); Frederick W. Goldberg (Editor); Cancer Research Uk (Other)
- Encuadernación Tapa dura
- Número de edición 1st
- Edición 1
- Páginas 332
- Volúmenes 1
- Idioma ENG
- Editorial Royal Society of Chemistry
- Fecha de publicación 2012
- Ilustrado Sí
- Features Bibliography, Illustrated, Index, Table of Contents
- ISBN 9781849731744 / 1849731748
- Peso 1.41 libras (0.64 kg)
- Dimensiones 9.41 x 6.4 x 0.91 pulgadas (23.90 x 16.26 x 2.31 cm)
-
Temas
- Aspects (Academic): Biotechnology Aspects
- Dewey Decimal Code 615.792
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Kinase Drug Discovery
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Royal Society of Chemistry RSC , pp. 332 Illustrated Edition . Hardback. Used.
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Kinase Drug Discovery
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Kinase Drug Discovery (Rsc Drug Discovery)
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Royal Society of Chemistry, 2011. Hardcover. New. 1st edition. 318 pages. 9.75x6.50x1.00 inches.
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KINASE DRUG DISCOVERY (HB 2012)
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USA Edition . Brand New. New. Ship within 24hrs. Satisfaction 100% guaranteed. I Ships from multiple Locations I ""Special Note"" We do not Provide Service On APO & PO BOX Box addresses. Delivery with In 7-14 working Day Only. This Books ship from the United Kingdom & USA other locations in India depending on your location and availability.
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USA Edition . Brand New. New. Ship within 24hrs. Satisfaction 100% guaranteed. I Ships from multiple Locations I ""Special Note"" We do not Provide Service On APO & PO BOX Box addresses. Delivery with In 7-14 working Day Only. This Books ship from the United Kingdom & USA other locations in India depending on your location and availability.
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