Bacterial Virulence Factors and Rho Gtpases Tapa dura - 2005

Primera línea

There are approximately 100 pathogenic microbes that cause significant disease in humans, accounting for one-third of all deaths on the planet, in addition to many other pathogens that infect other mammals, animals, and plants.

Descripción de contraportada

Pathogenic bacteria for human and animals have developed sophisticated weapons, termed virulence factors, to ensure their replication and persistence into their hosts. The first role of these virulence factors is to loosen the host defenses against microorganisms represented by innate and adaptive immunities. Small GTPases of the Rho subfamily have been shown top play important functions in theses systems.

The authors of this volume present the synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfill their virulence.