Intracellular Traffic and Neurodegenerative Disorders Tapa dura - 2008 - 1st Edición
de Peter H. St George-Hyslop (Editor); William C. Mobley (Editor)
Descripción de contraportada
This book explores the role of sub-cellular trafficking in the pathogenesis, treatment and prevention of neurodegenerative diseases. Recent findings point to faulty trafficking as contributing to the dysfunction and degeneration of neurons and neural circuits. Increasingly, research is targeting the mechanisms responsible and means to address them therapeutically. Many adult onset neurodegenerative diseases appear to arise from the accumulation of misfolded, neurotoxic peptides. This book investigates the ways in which sub-cellular trafficking pathways play a role both in the pathological accumulation of these misfolded proteins and in attempts to clear them. Because subcellular protein trafficking has an important role in the biology of neuronal function and survival, this also addresses how trophic factors maintain cell: cell interactions and how the underlying mechanisms may be compromised in neurodegenerative diseases. Examples where the use of such trophic factors may provide a way to modify neurodegenerative diseases are investigated.
Detalles
- Título Intracellular Traffic and Neurodegenerative Disorders
- Autor Peter H. St George-Hyslop (Editor); William C. Mobley (Editor)
- Encuadernación Tapa dura
- Número de edición 1st
- Edición 1
- Páginas 184
- Volúmenes 1
- Idioma ENG
- Editorial Springer
- Fecha de publicación 2008-12-10
- Ilustrado Sí
- Features Bibliography, Illustrated, Index, Table of Contents
- ISBN 9783540879404 / 3540879404
- Peso 0.9 libras (0.41 kg)
- Dimensiones 9.4 x 6.2 x 0.5 pulgadas (23.88 x 15.75 x 1.27 cm)
- Número de catálogo de la Librería del Congreso de EEUU 2008936139
- Dewey Decimal Code 616.804
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