Mechanistic Studies of Drug-Disease and Drug-Drug Interactions Tapa blanda - 2009

New. New Book; Fast Shipping from UK; Not signed; Not First Edition; The Mechanistic Studies of Drug-Disease and Drug-Drug Interactions.

Paperback / softback. New.

paperback. Good. Access codes and supplements are not guaranteed with used items. May be an ex-library book.

Internal pages are in excellent conditions, without any seal, writing, stain or rip. Just like new. The edges show minor wears. We will wrap the product carefully, and ship it from Japan. All our products are briefly disinfected and sealed in a waterproof envelope. Every minute, we are exposed to and involuntarily absorb xenobiotics which may produce beneficial outcomes or harmful effects on our bodies. Drug metabolism is initially a defensive mechanism driven by certain enzymes to facilitate excretion and in turn reduce the body burden of the absorbed xenobiotics. However, the capacity of this protective system is regulated by factors including disease states, absorbed xenobiotics and genetic factors. Cytochrome P450 3A4 (CYP3A4) is the most abundant phase I drug metabolism enzyme in human liver and its expression levels affect the capacity of drug metabolism. In this book, mechanisms have been investigated on regulation of CYP3A4 gene expression through modulating pregnane X receptor… Leer más